Researchers at Pitt have produced the most detailed image to date of a bacteriophage, or phage — a kind of virus that kills bacteria — that has allowed them to see for the first time the structural makeup of the part of the virus that directly attaches to its target Mycobacterium cell. The work could enable new therapies that use bioengineered phages.
“Now you've got like a spec sheet for going in and designing phages so that they’ll bind to different kinds of cells,” said Graham Hatfull, the Eberly Family Professor of Biotechnology in the Kenneth P. Dietrich School of Arts and Sciences.
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